Implementation of Meniran Extract (Phyllanthus Niruri Linn) on the Performance of Broiler Chickens Infected by Mycoplasma gallisepticum Caused Chronic Respiratory Disease

Abstract

Chronic respiratory disease (CRD) of chicken is a disease that has great economic losses in poultry industry in the world. The losses are mainly due to the decrease of body weight gain, feed efficiencies, hatchabilities and increase conversion of the feed, of embryo mortality. The main causative agent of Chronic Respiratory Disease (CRD) is Mycoplasma gallisepticum. Mycoplasma gallisepticum attacks the respiratory tract, especially in young broiler chickens with age ranged 3-5 weeks. CRD treatment usually uses macrolide antibiotics, because it has proven effective to inhibit protein synthesis. However, it is not recommended to continuously given because the chicken can be resistant to the medicineand leave a harmful reside to consumers. The development of herbal medicine utilization currently is mostly implemented for the treatment of diseases that infected livestock. Meniran plants (Phyllanthus niruri Linn) is one of the plants that can be used as prevention and alternative treatment caused by Chronic Respiratory Disease (CRD). Meniran (Phyllanthus niruri Linn) has the content of bioactive compounds that have antibacterial activity, including terpenoids,alkaloids, flavonoids, saponins, and tannins. The purpose of this study is to test and evaluate the effectiveness of Meniran extract (Phyllanthus Niruri Linn) on the performance of broiler chickens infected by Chronic Respiratory Disease (CRD), seen from the feed conversion.

Keywords: Meniran, Mycoplasma galisepticum, Chronic Respiratory Disease (CRD), performance of Broiler Chickens, Feed Conversion

References
(1) Adams, C.A. 2000. The Role of Nutricines in Health and Total Nutrition. Proc. Aust. Poult. Sci. Sym. 12: 17-24.
(2) Assidqi K, Wahyu T, dan Setyawati S, 2012. Potensi Ekstrak Daun Patikan Kebo (Euphorbia hirta) sebagai Antibakteri Terhadap Aeromonas hydrophila Secara In Vitro .Journal of Marine and Coastal Science, 1 (2):113-124.
(3) Barnes HJ and Yoder HW. 1984. Disease of Poultry. 8th ed. Iowa State University Press.
692-708
(4) Bell, D.D and W. D. Weaver., 2002. Commercial Chicken Meat and Egg Production.4th Ed. Kluver Academic Publishers. USA.
Bokhari SA. Mycoplasma gallisepticum infection and prevention. Avian Research Center, University of Minnesota. Available at: http://www.cvm.umn.edu/avian/SFPC/Mycoplasma.html*. Accessed 17 March 2003.
(5) Butcher GD. 2002Mycoplasma gallisepticum - a continuing problem in commercial poultry (VM130). Veterinary Medicine-Large Animal Clinical Sciences Department, Florida Cooperative Extension Service, Institute of Food and Agricultural Sciences, University of Florida
(6) Cotran RS, V Kumar and T Collins. 1999. Diseases of Immunity in Robbins Pathologic Basis of Disease. Sixth Edition, Pages: 188 - 259. WB Saunders Company, A Division of Harcourt Brace & Company, The Curtis Center Independence Square West Philadelphia, Pennsylvania 19106
(7) Ferguson-Noel NM Laibinis VA and Kleven SH 2012. Evaluation of Mycoplasma gallisepticum K-Strain as a Live Vaccine in Chicken. Avian Diseases. Vol.56 No.1
(8) Gunal, M. 2006. The Effect of Antibiotic Growth Promoter, Probiotik or Organic Acid Supplementation on Performance, Intestinal Microflora and Tissue of Broilers. International. Journal of Poultry Science 5 (2):149-155.
(9) Gunawan IGW, Gede Bawa IGA, Sutrisnayanti NL, 2008. Isolasi dan Identifikasi Senyawa Terpenoid yang Aktif Antibakteri pada Herba Meniran (Phyllanthus Niruri Linn). Jurnal Kimia, 2 (1): 31-39
(10 ) Harborne, J. 1987. Metode Fitokimia, Edisi Kedua. ITB. Bandung
(11) Kompiang, I.P1. 1993. Formulasi Pemberian dan Evaluasi Pakan Unggas.Forum Komunikasi Hasil Penelitian Bidang Peternakan.Yogyakarta.
(12) Ley DH. Mycoplasma gallisepticum infection. In Calnek BE, HJ Barnes, CW Beard, LR
McDougald, YM Saif, editors. Diseases of poultry. 11th ed. Ames, Iowa: Iowa State University Press; 2003. p. 722-744.
(13) Mathivanan R, SC Edwin, R Amutha and K Viswanathan. 2006. Panchagavya and Andrographis Panicuata as Alternative to Antibiotic Growth Promoter on Broiler Production and Carcass Characteristic. India. Departement of Poultry Science, Veterinary College and Research Institute. Namakkal-637001.
(14) Maynard, L.A. Loosil, J.K Hintz, H.F and Warner, R.G., 2005. Animal Nutrition. (7th edition) Mcgrow-Hill Book Company. New York, USA.
(15) McDonald, P,. R.A. Edward, and J.F.D Greenhalgh. 1994. Animal Nutrition. Fourth Edition.Longman Scientific and Technical. London

(16) Murtidjo, B.A. 1987. Pedoman Beternak Ayam Broiler. Cetakan Pertama. Kanisius, Yoyakarta
(17) North, M. O and D. D. Bell. 1990. Commercial Chicken Production Manual. 4th Ed. Chapman and Hall. New York
(18) Saif. 2003. Disease of Poultry 11th Ed. Iowa : BlackWell.
(19) Soeripto. 2009. Chronic Respiratory Disease (CRD) pada ayam. Jurnal Martazoa. Vol. 19 no.3
(20 Sreenivas, P. 1999. Herbal Healing. Far Eastern Agriculture, September/October 1999. pp. 31-32.
(21) Sudarno, Setiorini FA, dan Suprapto H. 2011. Efektifitas Ekstrak Tanaman Meniran (Phyllanthus niruri) Sebagai Antibakteri Edwardsiella tarda Secara In Vitro. Jurnal Ilmiah Perikanan dan Kelautan. 3 (1): 103-108.
(22) Sutton S, 2011. Measurement of Microbial Cells by Optical Density. Journal of Validation Technology. 17: 46-49.
(23) Taylor, L. 2006. Chanca Piedra (Phyllanthus niruri). Available from: URL: http://www.rain-tree.com/index.html. 25/1/07
(24) Wahju, J. 2004. Ilmu Nutrisi Unggas. Cetakan ke lima. Gadjah Mada University Press, Yogyakarta
(25) Zainuddin, D. 2010. Tanaman Obat Meningkatkan Efisiensi Pakan dan Kesehatan Ternak Unggas.Hasil Penelitian Desmayati Zainuddin Balai Penelitian Ternak Jl. Veteran – III PO Box 221, Bogor 16002